A Handbook for DNA-Encoded Chemistry Theory and Applications for Exploring Chemical Space and Drug Discovery

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry - synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

ISBN:	9781118487686
Publisher:	Wiley
Imprint:	John Wiley & Sons, Inc.
Published date:	08 Aug 2014
DEWEY:	615.19
DEWEY edition:	23
Language:	English
Number of pages:	xxv, 453 , 16 unnumbered of plates
Weight:	820g
Height:	164mm
Width:	237mm
Spine width:	31mm

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